Geissoschizine methyl ether
Geissoschizine methyl ether
CAS: 60314-89-8
Molecular Formula: C22H26N2O3
Geissoschizine methyl ether - Names and Identifiers
Geissoschizine methyl ether - Physico-chemical Properties
| Molecular Formula | C22H26N2O3 |
| Molar Mass | 366.45 |
| Density | 1.23±0.1 g/cm3(Predicted) |
| Boling Point | 542.0±50.0 °C(Predicted) |
| Solubility | Soluble in methanol, DMSO, chloroform, acid water |
| Appearance | White powder or crystal |
| pKa | 18.02±0.40(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Sensitive | Avoid light |
| MDL | MFCD30725476 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Uncaria. |
Geissoschizine methyl ether - Reference
| Reference Show more | 1. [IF=4.759] Keyu Feng et al."Configuration of the ion exchange chromatography, hydrophilic interaction chromatography, and reversed-phase chromatography as off-line three-dimensional chromatography coupled with high-resolution quadrupole-Orbitrap mass spectrometry fo 2. [IF=6.529] Lingling Xie et al."Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway."Biomed Pharmacother. 2022 Feb;146:112607 |
Geissoschizine methyl ether - Reference Information
| Overview | Uncaria is a plant of the genus Uncaria (Uncaria) in the Rubiaceae (Rubiaceae), and the main active ingredient is alkaloids, such as rhynchophylline (rhynchophylline), Isorchophylline (isorhynchophylline), etc. Uncaria is a commonly used medicine in traditional Chinese medicine, which has the effects of clearing heat and calliding the liver, relieving wind and setting alarm, and lowering blood pressure. |
| biological activity | Geissoschizine methyl ether, an alkaloid compound found Uncaria hook, is also the main active ingredient of Yokukansan with psychotropic drugs. Geissoschizine methyl ether is an agonist of the potent 5-HT1A receptor. |
| target | 5-HT 1A Receptor |
| chemical properties | white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from uncaria. |
| use | rhynchophylline has anti-platelet aggregation, anti-thrombosis and blood pressure lowering effects. used for content determination/identification/pharmacological experiment, etc. |
Last Update：2024-04-10 22:29:15
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Product Name: Geissoschizine methyl ether Visit Supplier Webpage Request for quotationCAS: 60314-89-8
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Mobile: 18021002903
QQ: 3008007409
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